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THE KOREAN LIVER CANCER ASSOCIATION
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Case Report
- Adult hepatoblastoma: making the challenging distinction from hepatocellular carcinoma
- Allison Kaye L. Pagarigan, Paulo Giovanni L. Mendoza
- J Liver Cancer. 2023;23(1):219-224. Published online March 13, 2023
- DOI: https://doi.org/10.17998/jlc.2023.02.24
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Abstract
PDF - Hepatoblastoma is an exceptionally rare malignancy in adults with just over 70 non-pediatric cases reported in literature. Recounted is a case of a 49-year-old female who presented with acute right upper quadrant abdominal pain, elevated serum alpha fetoprotein and a large liver mass on imaging. Hepatectomy was performed under clinical suspicion of hepatocellular carcinoma. Immunomorphologic characteristics of the tumor proved consistent with hepatoblastoma of mixed epithelial and mesenchymal type. Hepatocellular carcinoma remains to be the primary differential diagnosis for adult hepatoblastoma, however, distinguishing between these two neoplasms requires close histomorphologic assessment and immunohistochemical profiling as clinical, radiologic and gross pathologic findings typically overlap. Making this distinction is highly crucial in the timely initiation of surgical and chemotherapeutic interventions for this inherently aggressive and rapidly fatal disease.
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Citations
Citations to this article as recorded by
- Clinical and Pathological Spectrum of Hepatoblastoma with Emphasis on Treatment-Induced Changes: Experience from Tertiary Care Center
Divya Achutha Ail, Malini Eapen, Pavithran Keechilat, Sudheendran Surendran, Naveen Viswanath
Indian Journal of Medical and Paediatric Oncology.2025;[Epub] CrossRef - Blastomas of the digestive system in adults: A review
Yu Liu, Tony El Jabbour, Jonathan Somma, Yukihiro Nakanishi, Saverio Ligato, Hwajeong Lee, Zhi-Yan Fu
World Journal of Gastrointestinal Surgery.2024; 16(4): 1030. CrossRef - Adult Hepatoblastoma and Concomitant Hepatitis B Infection
Alejandro Nieto Dominguez, Sarah Elizabeth Eichinger, Elza Matrova, Anas Almoghrabi
ACG Case Reports Journal.2024; 11(9): e01491. CrossRef
- Clinical and Pathological Spectrum of Hepatoblastoma with Emphasis on Treatment-Induced Changes: Experience from Tertiary Care Center
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